Max

Cobalt Ferrero (voice)

Isidor Rabi

Carl

Mr. Universe

Gregory

Fletcher Demming (voice)

Frenchman (segment "The Ballad of Buster Scruggs")

Charlie Eppes

Lavash (voice)

Self

Timo (voice) / Timo / Mom-Bot (voice) / Timo / Dr. Watermelon Bawkings (voice)

Al Teller

Jason

Seth Goldstein

Zor-El

Jerry MacNamara

Bernard

Kent

Beck

Communist Writer

Kareem Abdul Lavash (voice)

Self