Jo Bennett

Delphine LaLaurie / Ethel Darling / Iris / Agnes Mary Winstead / Miriam Mead / Delphine LaLaurie

Annie Wilkes

Evelyn Couch

Gertrude Stein

Sylvia Simon

Mrs. Helen Givings

Roberta Hertzel

Prostitute

Rosemary

Helen Kushnick

Bitsy the Cow (voice)

Stella Mae

Ma James

Woman on Mateo Street

Susan

Sue

Ida Marquette

Leila Ford

Aunt Mitsy (uncredited)

Regina Jackson

Bryan's Mother

Det. Shirley Vogel

Sunny Soke